THE RESTORATION OF A BONE PERIODONTAL DEFECT WITH A BIOLOGICALLY ACTIVE MATRIX WITH HYALURONIC ACID AND PLATELET GROWTH FACTORS IN THE EXPERIMENT
DOI:
https://doi.org/10.35220/2078-8916-2020-36-2-10-16Keywords:
PRP growth factors, hyaluronic acid, regen-eration, neoangeogenesis, periodontal defectAbstract
A comparative analysis of the healing of a periodontal bone defect in the area of molars in the lower jaw using various types of biologically active materials, namely, a decellularized amniotic membrane, a decellularized am-niotic membrane in combination with PRP growth factors and a decellularized amniotic membrane in combination with PRP growth factors and hyaluronic acid, that regen-eration of a bone defect when suturing it with a mucous membrane in 2 months occurs in all comparison groups. But the quality of the resulting bone is very different in the number of blood vessels. So in the first group (con-trol) vessels are practically absent, and in groups 3 and 4 the presence of vessels is noted on the preparations al-ready from 14 days. Also, the process of formation of a newly formed bone itself occurs faster in groups 3 and 4 compared with groups 1 and 2. After morphological stud-ies, it is possible to recommend the use of biologically ac-tive materials in a combination of PRP and hyaluronic acid growth factors for the regeneration of oblique perio-dontal defects.
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