MORPHOLOGICAL CHARACTERISTICS OF PERIODONTAL TISSUES IN SYSTEMIC LUPUS ERYTHEMATOSUS
DOI:
https://doi.org/10.35220/2078-8916-2023-47-1.27Keywords:
systemic lupus erythematosus (SLE), periodontal morphology, connective tissue.Abstract
The aim of the study. The analysis of morphological changes in periodontal tissues was carried out in order to improve the diagnosis of pathological changes in the oral cavity in patients with SLE and to develop local pathogenetically determined treatment measures to improve the quality of life of this category of patients. Research methods. Microstructural changes of periodontal tissues were studied in 15 patients with SLE by means of morphological examination of biopsies. Scientific novelty. Systemic lupus erythematosus (SLE) is a disease from the group of diffuse diseases of the connective tissue, which develops on the basis of genetically determined imperfect immunoregulatory processes, which lead to the creation of multiple antibodies to cells and their components and the occurrence of immune complex inflammation, as a result of which a multiorgan pathology occurs, which affects also periodontal tissues and the oral mucosa (OSPR), which is manifested in the detected morphological changes. Conclusions. The morphological picture of periodontal tissues in systemic lupus erythematosus is characterized by dystrophy of the epithelial layer, collagen necrosis with the formation of Russel bodies, and signs of chronic gingivitis. Also signs of periodontal tissue damage in SLE are lymphocytic infiltration with plasma cell impurities, nuclear pathology and productive vasculitis.
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