SUBSTANTIATION OF THE RESULTS OF THE STUDY OF SUBCHRONIC TOXICITY OF A NEW DOMESTIC CAST PLASTIC MATERIAL FOR THE MANUFACTURE OF THE BASES OF COMBINED REMOVABLE ORTHOPEDIC STRUCTURES

Abstract

The arsenal of doctors and dental technicians lacks domestic construction materials for the manufacture of the bases of removable dental prostheses using the technology of casting pressing with compression polymerization. The development of such material opens up opportunities for dentists – orthopedists and orthodontists, regarding the quality treatment of a number of pathological conditions, acceleration of technological stages and full restoration of the function of the maxillofacial system at the stages of dental prosthetics, which was the goal of our further research. The purpose of our study was to analyze the results of a subchronic study of the properties of cast plastic material for the manufacture of bases of combined removable orthopedic structures using an improved method. Plastic of cold polymerization was used for the manufacture of denture bases. Results. The following indicators were analyzed: the results of the influence of the sample under study for 21 days on the body weight of white rats; influence on biochemical indicators of blood serum; influence on hematological parameters; indicators of the functional state of the kidneys in rats with long-term administration of VBPLP and the results of the influence of domestic cast base plastic on the state of the internal organs of the studied rats during 21 days of research. In terms of sanitary and chemical qualities, the developed material meets all the requirements of orthopedic dentistry and the available international ISO standards. Conclusions. As a result of the conducted study of subchronic toxicity, it was established that, in general, long-term administration of domestic cast base plastic does not have a negative effect on the organs and systems of experimental animals, does not cause suppression of general metabolic processes.