THE INTENSITY OF INFLAMMATION AROUND COMMERCIAL DENTAL IMPLANTS WITH DIFFERENT SURFACES
DOI:
https://doi.org/10.35220/2078-8916-2023-50-4.13Keywords:
implant, peri-implantitis, mucositis, microflora, microbiota, inflammation.Abstract
Purpose of the study. Definition of the frequency of inflammation in peri-implantitis around commercial implants with different methods of surface coating. Material and methods. A relatively equal number of 4 commercial screw intraosseous dental implants with different coatings, which have been on the Ukrainian market for more than 10 years and are widely used in dental practice, were used in the study. Peri-implant mucositis was diagnosed based on the results of probing. To identify the composition of the microbial flora and the degree of their contamination around the implants, in the presence of signs of peri-implantitis, fluid samples were taken from the pockets around the implants using a special sterile swab of a standard transport tube for inoculation with Ames medium. Results. The incidence of mucositis in the Xpeed group (16.0 %) was the lowest, but was significantly different from the 3D Active group (54.5 %), p=0.005; The differences between Xpeed and PEO (34.6 %) are not significant (p>0.05). Early detection of inflammation around implants indicated the presence of mainly saprophytic species of bacteria, including Klebsiella pneumoniae, with pathological concentrations of Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus viridans. Klebsiella pneumoniae was detected in both Xpeed (50.0 %) and 3D Active (8.3 %). High bacterial contamination was observed for 3D Active and DAE – 107 CFU/tampon and 108 CFU/tampon. Conclusion. According to the indicators of the frequency of damage to the mucous membrane around the implants, the implants with the Xpeed surface (16.0 %), p1=0.0042, p2=0.005 and p3=0.0013, were reliably more reliable. According to the clinical indicator of the severity of inflammation around the implants, implants with a PEO surface turned out to be reliable; mild mucositis was diagnosed around these implants more often (77.8 %) than others p=0.0011. The minimum diversity of bacterial species was around REO and DAE. Pathogenic bacterial contamination rates of 108 CFU/tampon and 107 CFU/ tampon were more common around DAE implants. In terms of the severity of bacterial invasion of tissues surrounding the implants, implants with a 3D Active and Xpeed surface were at a disadvantage due to the presence of Klebsiella pneumoniae in a large amount of 107 CFU/tampon and in a conditionally pathogenic amount of 104 CFU/tampon, respectively.
References
Saghiri, Mohammad Ali, Peter Freag, Amir Fakhrzadeh, Ali Mohammad Saghiri, and Jessica Eid. Current technology for identifying dental implants: a narrative review. Bulletin of the National Research Centre 45, no. 1 (2021). Gale Academic OneFile (accessed November 29, 2023). https://link.gale.com/apps/doc/A650805690/AONE?u=anon~1a66d02e&sid=googleScholar&xid=5ad559cd.
Elani, H.W.; Starr, J.R.; Da Silva, J.D.; Gallucci, G.O. (2018). Trends in Dental Implant Use in the U.S., 1999–2016, and Projections to 2026. J. Dent. Res., 97, 1424–1430.
Duminil, G., Muller-Bolla, M., Brun, J-P., Leclercq, Ph., Bernard, J-P., (2008). Dohan Ehrenfest Success Rate of the EVL Evolution Implants (SERF): A Five-Year Longitudinal Multicenter Study. J Oral Implantol., 34(5), 282–289. https://doi.org/10.1563/1548- 1336(2008)34[283:SROTEE]2.0.CO;2.
Solderer, A., Al-Jazrawi, A., Sahrmann, P., Jung, R., Attin, T,. Schmidlin, PR. (2019). Removal of failed dental implants revisited: Questions and answers. Clin Exp Dent Res., 5(6), 712-724 doi: 10.1002/cre2.234.
Dipanjan, Das, Nina Shenoy, Smitha Shetty. (2023). Understanding the Risk of Peri-Implantitis. Journal of Health and Allied Sciences NU doi https://doi.org/10.1055/s-0043-1766125.
Nguyen-Hieu, T., Borghetti, A., Aboudharam, G. (2012). Peri-implantitis: from diagnosis to therapeutics. J. Investig. Clin. Dent., 3, 79–94.
Renvert, S., Lindahl, C., Persson, GR. (2018) Occurrence of cases with peri-implant mucositis or periimplantitis in a 21–26 years follow-up study. J Clin Periodontol., 45(2), 233–240.
Jeon. J.H., Kim, M.J., Yun, P.Y., Jo, D.W., Kim, Y.K. (2022). Randomized clinical trial to evaluate the efficacy and safety of two types of sandblasted with large-grit and acid-etched surface implants with different surface roughness. J Korean Assoc Oral Maxillofac Surg.,
(4),225-231 doi: 10.5125/jkaoms.2022.48.4.225.
Bavetta, G., Bavetta, G., Randazzo, V., Cavataio, A., Paderni, C., et al. (2019). Retrospective Study on Insertion Torque and Implant Stability Quotient (ISQ) as Stability Parameters for Immediate Loading of Implants in Fresh Extraction Sockets. Biomed Res Int., 2019, 9720419 doi: 10.1155/2019/9720419.
Inchingolo, A.D., Inchingolo, A.M., Bordea, I.R., Xhajanka, E., Romeo, D.M., et al. (2021). Effectiveness of Osseodensification Drilling Protocol for Implant Site Osteotomy: A Systematic Review of the Literature and Meta-Analysis. Materials (Basel),. 14(5), 1147 doi: 10.3390/ma14051147.
Williams, J.C., Boyer, R.R. (2020). Opportunities and Issues in the Application of Titanium Alloys for Aerospace Components. Metals., 10(6), 705. https://doi.org/10.3390/met10060705.
López-Valverde, N., Macedo-de-Sousa, B., López-Valverde, A., Ramírez, J.M. (2021). Effectiveness of Antibacterial Surfaces in Osseointegration of Titanium Dental Implants: A Systematic Review. Antibiotics (Basel)., 10(4), 360. doi: 10.3390/antibiotics10040360.
Sindeeva, O.A., Prikhozhdenko, E.S., Schurov, I., Sedykh, N., Goriainov, S, et al. (2021). Patterned Drug-Eluting Coatings for Tracheal Stents Based on PLA, PLGA, and PCL for the Granulation Formation Reduction: In Vivo Studies. Pharmaceutics, 3(9), 1437 doi: 10.3390/
pharmaceutics13091437.
Mishhenko O.M. (2020). Kliniko-eksperymental'ne obg'runtuvannja novyh metodiv dental'noi' implantacii' pry vykorystanni implantiv z cyrkonijevyh splaviv [Clinical and experimental substantiation of new methods of dental implantation using zirconium alloy implants]. Extended abstract of Doctor’s Державний заклад " Dnipropetrovs'ka medychna akademija MOZ Ukrai'ny". Dnipro.
Rupp, F., Liang, L., Geis-Gerstorfer, J., Scheideler, L., Hüttig F. (2018). Surface characteristics of dental implants: A review. Dent Mater., 34(1), 40-57 doi:10.1016/j.dental.2017.09.007.
Costa-Berenguer X., García-García, M., Sánchez-Torres, A., Sanz-Alonso, M., Figueiredo, R., Valmaseda-Castellón, E. (2018). Effect of implantoplasty on fracture resistance and surface roughness of standard diameter dental implants. Clin Oral Implants Res., 29(1), 46-54 doi: 10.1111/clr.13037.
Katalinić, I., Smojver, I., Morelato, L., Vuletić, M., Budimir, A., Gabrić, D. (2023). Evaluation of the Photoactivation Effect of 3% Hydrogen Peroxide in the Disinfection of Dental Implants: In Vitro Study. Biomedicines, 11(4), 1002 doi: 10.3390/ biomedicines11041002.
Ehrenfest, D.M.D., Del Corso, M., Kang, B.S., Leclercq, P. (). Identification card and codification of the chemical and morphological characteristics of 62 dental implant surfaces. Part 3: Sand-blasted/acid-etched (SLA type) and related surfaces (Group 2A, main subtractive process) Poseido., 2:37–55
Labis, V., Bazikyan, E., Zhigalina, O., Sizova, S., Oleinikov, V., et al. (2022). Assessment of dental implant surface stability at the nanoscale level. Dent Mater., 38(6):924-934 doi: 10.1016/j.dental.2022.03.003.
Berglundh, T., Armitage, G., Araujo, M.G., Avila-Ortiz, G, et al. (2018). Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Clin Periodontol., 45, 20, S286-S291 doi: 10.1111/jcpe.12957.
de Waal, Y.C., Eijsbouts, H.V., Winkel, E.G., van Winkelhoff, A.J. (2017). Microbial Characteristics of Peri-Implantitis: A Case-Control Study. J. Periodontol., 88, 209–217 doi: 10.1902/jop.2016.160231.
Abranches, J., Zeng, L., Kajfasz, J.K., Palmer, S.R., Chakraborty, B., et al. (2018). Biology of Oral Streptococci. Microbiol. Spectr., 6, 426–434 doi: 10.1128/microbiolspec. GPP3-0042-2018.
Bhardwaj, B., Bhatnagar, U.B., Conaway, D.G. (2016). An Unusual Presentation of Native Valve Endocarditis Caused by Staphylococcus warneri. Rev Cardiovasc Med., 17(3-4), 140-143 doi: 10.3909/ricm0823.
Kensara, A., Hefni, E., Williams, M.A., Saito, H., Mongodin, E., Masri, R. (2021). Microbiological Profile and Human Immune Response Associated with Peri-Implantitis: A Systematic Review. J Prosthodont., 30(3), 210-234 doi: 10.1111/jopr.13270.
