MICROBIOLOGICAL SPECTRUM OF DENTAL PLAQUE IN CHILDREN WITH GASTROINTESTINAL TRACT DISEASES

Abstract

Purpose of the study. Determination of the microbiological spectrum and species composition of dental plaque in children with gastrointestinal tract diseases, taking into account rampant caries. Research methods. For clinical and laboratory studies were selected 120 children, of which was formed the main group – 80 children with rampant caries on the background of gastrointestinal tract diseases and a comparative group – 40 children with intact teeth with similar somatic gastrointestinal lesions. The material for microbiological examination was plaque. Scientific novelty. The frequency and degree of contamination of dental plaque in children with rampant caries was higher than in subjects with intact teeth and was characterized by the presence of speciesspecific microorganisms. First of all, it should be noted that with the presence of gastrointestinal lesions, specific microorganisms in the plaque of children of the main group were Helicobacter pylori. The maximum frequency of excretion was Lactobacterium 68.5% at a colonization density of 4.11 ± 0.12 lgKYO / ml, (p <0.001) in children with rampant caries. Gram-positive facultative Nocardia was identified in subjects of main group, and Gram-negative facultative Proteus was found 2.2 times more often than in subjects of comparative group. Conclusions. Expansion of the spectrum of microbial associations, significant prevalence of cariogenic microorganisms (Str.mutans, Str.sanguis, Lactobacterium) contributed to the progression of the pathological process and convincingly proves their pathogenetic effect in the development of rampant caries. It should be noted that the presence of Helicobacter pylori in plaque should be regarded as an additional pathogenetic mechanism of intensification of lesions of organs and tissues of the oral cavity.