RESULTS OF THE CYTOLOGICS RESEARCH AFTER SURGERY WITH GENERALIZED PERIODONTITIS ACOMPANED BY DIFFERENT REACTIVITY OF THE BODY
DOI:
https://doi.org/10.35220/2078-8916-2022-46-4.7Keywords:
generalized periodontitis, reactivity of the organism, postoperative wound, phases of healingAbstract
Purpose of the study. A cytological study of the intensity and duration of the phases of the wound process in patients with generalized periodontitis of II, III degrees of severity with normo-, hyper- and hyporeactivity of the body after the patch surgery according to indications. Materials and methods of research. 216 patients aged 45 between 55 years with the diagnosis of generalized periodontitis of II, III degrees of severity were examined. Depending on the condition of reactivity of the body, patients were divided into three groups: the first was made up by patients with normoreaction (132 people, 61%); the second group consisted of people with hyperreaction (46 people, 21%); the third included patients with hyporeaction (38 people, 18%). Patients underwent patch surgery according to the indications. Blood sampling was performed after the surgery on the 1st, 4th, 6th and 9th day. The phases of the wound process were determined by cytological examination by smear prints. Scientific novelty. The results of cytological examination showed that patients with generalized periodontitis with normoreactivity of the body after surgery are characterized by wound healing with three periods of cellular response: the period of initial degenerative changes (the 1st day), inflammation with active granulocytic and macrophage reactions (the 4th day) and the growth of reparative processes (the 6th day). In cases of hyperreactivity of the organism the granulocytic reaction developed more actively and lasted longer, later there were cellular signs of regeneration (the 9th day). In cases of hyporeactivity of the organism the granulocytic reaction came later and lasted longer, cellular signs of regeneration appeared later ( the 9th day). Conclusions. Bringing the phases of the wound process to those which are typical for normoreactivity of the body in patients with generalized periodontitis is considered to be a condition for optimizing the healing of mucosa and bone wound after surgery and further stabilization of the process in periodontal tissues.
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