IMPACT OF XENOGENEIC BONE SUBSTITUTES’ PARTICLE SIZE ON THE BONE TISSUE CHANGES IN THE AREA OF SUBANTRAL AUGMENTATION: RETROSPECTIVE LITERATURE ANALYSIS
DOI:
https://doi.org/10.35220/2078-8916-2022-44-2.17Keywords:
particle size, xenogeneic bone substitute, subantral augmentation.Abstract
Purpose of the study. To provide retrospective analysis of the potential impact of used xenogeneic bone substitutes’ particle size on the changes within the bone tissue in the area of subantral augmentation based on the previously provided studies. Research methods. The design of the study represented retrospective analysis of the literature, which included following stages: 1) formation of a target publications cohort from the PubMed database (https:// pubmed.ncbi.nlm.nih.gov/) using appropriate Mesh-terms and identification of such publications also in Google Scholar (https://scholar.google.com/) using keywords search tools; 2) selection of publications from the target cohort for a detailed content analysis based on the results of annotations processing; 3) analytical processing and content analysis of textual information of scientific articles included in the targeted sample. Scientific novelty. The retrospective analysis provided structurization and refinement of the data regarding the influence of physical characteristics of the particle size of xenogeneic origin bone substitutes on quantitative and qualitative changes within bone tissue in the area of provided subantral augmentation procedure, as the most adapted clinical and experimental model. Conclusions. Due to the provided retrospective analysis of clinical and experimental studies use of xenogeneic bone substitutes with particles size of 1–2 mm and 0,25–1 mm during the subantral augmentation characterized by the similar results regarding the formation of new bone volume and reduction of graft residue during several months of monitoring. Higher osteoconductive and osteopromotional characteristics of small xenogeneic material particles, which have been verified in experimental and laboratory studies, were not associated with better results of subantral augmentation while comparing with the outcomes of using large sized particles according to the clinical studies data and based on the results of histological and microCT analysis.
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